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Abemaciclib plus fulvestrant in treating hormone-receptor positive, HER2-negative advanced breast cancer—comparing real-world outcomes in England to the MONARCH-2 trial - British Journal of Cancer
16+ hour, 7+ min ago (899+ words) British Journal of Cancer (2026)Cite this article Abemaciclib plus fulvestrant was approved in Europe following publication of the MONARCH-2 trial and recommended to enter the NICE Cancer Drugs Fund for HR+/HER2" advanced breast cancer. We aimed to assess MONARCH-2 generalisability…...
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1+ hour, 42+ min ago (16+ words) Algicidal bacteria as an eco-friendly mitigation of microalgae: an application paradigm shift to heritage conservation'Nature...
An atlas to navigate environmental factors and health - Nature Medicine
16+ hour, 7+ min ago (248+ words) Nature Medicine (2026)Cite this article We have systematically mapped the exposome onto health and disease risk to replace pervasive fragmented research. Although exposure associations are modest, these reproducible patterns reflect how our surroundings can affect our bodies and collectively shape…...
REP-1 deficiency induces aberrant mitochondrial metabolic rewiring from glycolysis to lipid oxidation in CHM disease - Cell Death & Disease
39+ min ago (1674+ words) Cell Death & Disease , Article'number:' (2026) Cite this article All datasets generated or analyzed during this study are included in the published article. Any additional information required to reanalyze the data reported in this paper is available from the lead contact upon…...
Understanding how destination attributes shaping tourist visitation on cultural routes through social media data and interpretable machine learning - npj Heritage Science
16+ hour, 7+ min ago (1712+ words) a Study area; b Keywords associated with the Kumano Kodo from related X posts 20102025. The methodological framework of this study consists of three main stages, as illustrated in Fig. 2. Firstly, using cleaned Flickr social media data and multi-source spatial datasets,…...
The heterogeneous integration of electronic components - Nature Reviews Electrical Engineering
2+ hour, 40+ min ago (1696+ words) Das Sharma, D. & Mahajan, R. V. Advanced packaging of chiplets for future computing needs. Nat. Electron. 7, 425427 (2024). Iyer, S. S. Chips, dies, chiplets and dielets and heterogeneous integration. In Proc. 2022 6th IEEE Electron Devices Technology & Manufacturing Conference (EDTM) 811 (IEEE, 2022). Zhang, K. 1.1 Semiconductor industry: present & future. In Proc. 2024 IEEE…...
Housing for well-being with minimal energy and material demand - Nature Reviews Clean Technology
1+ hour, 18+ min ago (1689+ words) Nature Reviews Clean Technology (2026)Cite this article The high well-being with low demand (HwL) housing concept is rooted in enabling decent living standards while remaining within global ecological limits. Housing energy and resource use values in the literature are up…...
The NPR1 agonist antibody XXB750 in heart failure: a phase 2 randomized trial - Nature Medicine
1+ hour, 21+ min ago (885+ words) Nature Medicine (2026)Cite this article Therapies targeting the natriuretic peptide system have the potential to reduce death or heart failure events in heart failure with reduced ejection fraction. Here we assess XXB750, a human monoclonal antibody activating natriuretic peptide receptor 1, in…...
Neuron–eosinophil circuit explains stress-induced eczema flares - Nature Reviews Immunology
16+ hour, 7+ min ago (339+ words) Neuron'eosinophil circuit explains stress-induced eczema flares'Nature Your privacy, your choice We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media, as well as to…...
Changes in body mass index and waist circumference as predictors of incident prediabetes: the Aichi Workers’ Cohort Study - Scientific Reports
2+ hour, 2+ min ago (1044+ words) The median age of the participants was 46 years (interquartile range [IQR] 4151). Of the 2,754 participants in this study, 72.3% were men. Baseline characteristics across BMI-change slope tertiles (in kg/m" per year) are presented in Table1. Significant differences across BMI-change slope tertiles were…...